The physiological homeostasis of human populations in variable environments.

A close evolutionary relationship of physiology and ecology of organisms determines the dynamic dependence of the population physiological status in man on ecological factors. For the explanation of the stability and variability of population physiological status the concept of physiological homeostasis was applied. The investigation of physiological status in several populations of Middle Asia, Kazakhstan, North-East Asia and Khakassia has shown that reversible changes in the environment may temporarily destabilize the equilibrium in the "population-environment" system and prolonged stresses may cause a state of disadaptation. For estimation of population physiological homeostasis dependent on the environment, generalized dispersion, correlation and factor analyses are very informative. They not only mark the violation of population homeostasis, but also indicate changes in the environment.